EXPLORE THE POWER
OF 3D SCREENING
Technology
Highlights
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Drug distribution closely mimic the distribution across the several cellular layers - simulating realistic scenarios.
UNLIMIT YOUR RESEARCH
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Long tissue life span, allowing chronic exposure scenarios for research.
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Authentic cytoarchitecture and cell interactions/function
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Capturing in vivo complexity
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Medium-to-low throughput
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Human background
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Production volume meets industry requirements
Unlimited source due to pluripotent stem cell origin
TOXICITY IN 3D MINIBRAIN SYSTEMS
Custom model developments
We assess toxicity on neural
3D tissues of different composition
Option 1
Option 2
Option 3
MiniBrains with strictly defined ratio of human neurons and human astocytes resulting from a mixture of cells from individual cell lines . Upon request, we are happy to pursue other cell line developments (e.g. microgila, microvessels, tumors and immune cells) in individual projects.
TOXICITY TESTING IN
100% PURE NEURONAL MINIBRAINS
Viablity assessed via resazurin reduction assay
EXPLORE CUSTOMIZABLE TESTING
FOR ANTI CANCER DRUGS
Glioblastoma Spheroids
Different sizes of tissues and spheroids available.
Anti-cancer drug testing in 3D gliobalstoma spheroids and 3D tumor tissues.
Spheroids and tissue produced out of wild type human glioblastoma cell line.
Various modification of human glioblastoma lines could be generated upon reques. Example: human glioblastoma line expressin mCherry fluorescen protein.